Target organ damage usually refers to the damage caused to the organs wherever the circulatory system feeds. The main target organs are kidney, heart, brain, and eyes. Hypertension causes early changes in organ systems as left ventricular hypertrophy, proteinuria, renal failure, retinopathy and vascular dementia. There are many steps involved in the act of target organ damage as platelet activation, endothelial activation, increased thermogenesis, changes in the renin-aldosterone-angiotensin system (RAAS) and collagen turnover.
- Track 1-1 Left Ventricular Hypertrophy
- Track 2-2 Proteinuria and Renal Failure
- Track 3-3 Retinopathy
- Track 4-4 Vascular Dementia
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